Researchers Prof. Judith Haendeler from the Medical Faculty and the molecular biologist Prof. Joachim Altschmied from the Department of Biology, together with their teams, have
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Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity
Self-amplifying RNA (saRNA) is an advanced platform for nucleic acid vaccine development. The backbone is typically derived from an alphaviral genome and encodes a gene
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Protein tenascin-C important in retinal blood flow disorders
Many eye diseases are associated with a restricted blood supply, known as ischaemia, which can lead to blindness. The role of the protein tenascin-C, an
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Blocking a protein in liver cells protects against insulin resistance, fatty liver disease
A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in
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Researchers show how low-protein diet during pregnancy can cause kidney problems in babies
Besides being underweight, babies born to women whose diet lacked sufficient protein during pregnancy tend to have kidney problems resulting from alterations that occurred while
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CityU researchers identify super-enhancers that stimulate the activity of breast cancer genes
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the
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New polypeptide could provide universal protection against coronaviruses
Researchers in the United States have developed an inhibitor of the spike protein found on the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that
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More new SARS-CoV-2 variants are highly likely
In a recent report posted to the bioRxiv* preprint server, researchers from the United Kingdom and Uganda reveal unique protein features of severe acute respiratory
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Temple, Case Western scientists receive $3 million NIH grant to study pathway behind heart failure
Like a bad water pump that fails to circulate coolant in a car engine, a failing heart struggles to pump blood through the body, causing
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Researchers report on novel SARS-CoV-2 Israeli strain with unique spike glycoprotein
In a recent medRxiv* preprint report, a research group from Israel described a novel SARS-CoV-2 strain with a non-synonymous mutation in its spike glycoprotein, designated
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